Impact of Malaria Parasitemia on Some Liver Enzymes among Adults Patients Attending University of Maiduguri Teaching Hospital, Maiduguri, Borno State-Nigeria

Abstract

Nearly half of the world's population is susceptible to malaria, a potentially fatal disease. When the parasite infection is left untreated or treated incorrectly, it can lead to catastrophic side effects such as chronic renal disease, liver illness, and even death. The goal of this study was to examine the blood and liver enzymes of UMTH, Maiduguri's malaria patients. The ALP, AST, and ALT of the malaria parasite were measured using conventional techniques. In this study, 125 malaria patients at the UMTH were divided into groups according to their sex, age, gender, and malaria density. Their ALP, AST, and ALT blood liver enzyme levels were examined and compared to those of 125 control patients. The research found that the majority of malaria patients Thirty-eight (30.4%) of the malaria patients, or (58.4 percent) of the total population, were males and were between the ages of 25 and 31. They predominantly have low malaria densities (+). The mean ALP, AST, and ALT values for malaria patients were 5.801, 12.760, and 20.470, respectively. This difference was extremely significant (P 0.05). Our research revealed 2.995, 2.056, and 3.594 as very significant differences in liver enzymes. The average levels of ALP, AST, and ALT in malaria patients with (+) were 7.178, 1.854, and 7.345, respectively. indicated a significant statistical difference when compared to patients with malaria who had (++) (p 0.05/0.01). In comparison to age groups 18-24 years, 25-31 years, 32-38 years, and 39-45 years, the value of liver enzymes in malaria patients showed no significant changes at 0.621U/L, 0.120U/L, and 0.496U/L, respectively. However, as previously mentioned writers have noted, that more work must be done to implement control strategies and eradicate malaria infection in this area.