Cytokine Status of Salivary Fluid in Patients with Coronavirus Infection
Keywords:
cytokines, interleukin-1 beta, TNF-α, saliva, COVID-19Abstract
Purpose: The article presents the results of a study of 2 major cytokines interleukin-1 beta and TNF-α in 30 patients with COVID-19, depending on the severity.
Materials and methods: Immunological studies were carried out on 30 saliva in patients with moderate and severe COVID-19 at the Republican Specialized Center No. 2 for coronavirus infection in 2020. All studies were carried out in the laboratory of immunocytokines of the Institute of Immunology of the Academy of Sciences of the Republic of Uzbekistan.
Results: 1. Analysis of interleukin in patients with IL-1 beta in patients with COVID-19 showed that in the group of moderate patients, the concentration was increased by 2 times, and in the group of severe patients - by 2.7 times. A significant increase in TNF-α production in saliva was also found in patients with moderate and severe COVID-19 by 2.8 times and 4.9 times, respectively.
Conclusion: Increased values of IL-1 beta and TNF-α in saliva in patients with moderate and severe COVID-19 prove the presence of a current inflammatory process in this case and in the oral cavity.
Downloads
References
F. U. Zhabborova. Adaptive mechanisms of local immunity of the oral mucosa in coronavirus infection//. Procuding of internat ional conference. Hosted from Telavi. Ceorgiya 17-18 March. 2021. 186-187 pp
F. U. Zhabborova. Local immunity of the oral mucosa in coronavirus infection//. Internat ional conference. Education and Science 2021. 203-204 pp
F. U. Zhabborova. Adaptive mechanisms of local immunity of the oral mucosa membrane of the cavity during in coronavirus infection//. Journal NX 2021.100-102pp
Bogatov A. I. Our method of treatment of periodontal diseases in children with cerebral palsy. // Samar. med. Journal. 2001. N 4. C. 44
Eronov E. K., Mirsalihova F.L., Ragabov A.A. Prevention and treatment of caries in children with cerebral palsy. ACADEMICIA: AnInternational Multidisciplinary Research Journal Vol. 9 Issue 12, December. 2019.–рр. 68-70. Impact factor- 7.13
Eronov E. K., Ragabov A.A. Assessment of the evaluation of oral hygiene in children with cerebral palsy. Asian Journal of Multidimensional Research (AJMR)Vol. 9 Issue 2 February 2020. – рр.189-191.Impact factor- 6.88.
Eronov E. K., Ragabov A.A.Analytical indicator of saliva in children with cerebral palsy. ACADEMICIA: An International Multidisciplinary Research Journal Vol. 10 Issue5 2020. – рр. 1823-1825. Impact factor- 7.13
Published
How to Cite
Issue
Section
This work is licensed under a Creative Commons Attribution 4.0 International License.
The work simultaneously licensed under a Creative Commons Attribution 4.0 International License
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
-
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
