Experimental Model of Knee Osteoarthritis in Rats on the Background of Intra-Articular Administration of Platelet-Enriched Autologous Plasma
Keywords:
Platelet-Enriched, PlasmaAbstract
Deforming osteoarthritis is a heterogeneous group of joint diseases of various etiologies, but with identical biological, morphological and clinical signs and outcome associated with loss of hyaline cartilage and concomitant damage to other anatomical structures and tissues of the joint (subchondral bone, synovial membrane, ligaments, joint capsule, per articular tendons and muscles). Hyaline cartilage contains a relatively small number of cells surrounded by a large amount of intercellular matrix. Chondrocytes are involved in the regulation of synthesis and degradation of cartilage matrix components, and normally these processes are in equilibrium
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