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GENERAL CHARACTERISTICS OF CLINICAL MATERIAL AND METHODS OF INVESTIGATION OF PATIENTS WITH PNEUMONIA COVID19

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Abstract

The main target of SARS CoV-2 is the lungs. In pathogenesis, 2 mechanisms should be distinguished that mutually burden each other and can lead to the development of ARDS (pathomorphologically diffuse alveolar damage): direct viral damage to alveocytes with the development of immuno-inflammatory syndrome; the development of micro- and macrothrombosis of pulmonary vessels and obstructive thrombo-inflammatory syndrome. Therefore, the disease was named microCLOTS – microCOVID Lung Obstructive Trombovascular Syndrome1. As in the whole world, the incidence of COVID 19 pneumonia in the Republic of Uzbekistan is more than 193,000 people, while there is a steady increase.2 The severity and severity of the clinical manifestations of COVID-19 depends on the massiveness of infection (the infecting dose of the virus) on the one hand and the individual characteristics of the macroorganism on the other (age, gender, strength of the immune response, the presence of concomitant diseases-risk factors, etc.). In radiation diagnostics, various variants of changes in the lungs in patients with confirmed coronavirus pneumonia detected using various methods of medical imaging (computed tomography, magnetic resonance imaging, X-ray and ultrasound diagnostics) during primary radiation examination are considered [2.4.6.8.9].

Abstract

The main target of SARS CoV-2 is the lungs. In pathogenesis, 2 mechanisms should be distinguished that mutually burden each other and can lead to the development of ARDS (pathomorphologically diffuse alveolar damage): direct viral damage to alveocytes with the development of immuno-inflammatory syndrome; the development of micro- and macrothrombosis of pulmonary vessels and obstructive thrombo-inflammatory syndrome. Therefore, the disease was named microCLOTS – microCOVID Lung Obstructive Trombovascular Syndrome1. As in the whole world, the incidence of COVID 19 pneumonia in the Republic of Uzbekistan is more than 193,000 people, while there is a steady increase.2 The severity and severity of the clinical manifestations of COVID-19 depends on the massiveness of infection (the infecting dose of the virus) on the one hand and the individual characteristics of the macroorganism on the other (age, gender, strength of the immune response, the presence of concomitant diseases-risk factors, etc.). In radiation diagnostics, various variants of changes in the lungs in patients with confirmed coronavirus pneumonia detected using various methods of medical imaging (computed tomography, magnetic resonance imaging, X-ray and ultrasound diagnostics) during primary radiation examination are considered [2.4.6.8.9].

Keywords

coronavirus infection
saliva lysocin
microbiocenosis of the oral cavity
neurostomatological syndromes
periodontitis
gingivitis

Declarations

Conflict of Interest Statement

The author (s) declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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References

1. Jonibekov J.J., Ismailova M.Kh. Role of computer tomography in diagnostics of coronaviral etiology of pneumonia // Journal of Hunan University(Natural Sciences)Vol. 48. No. 7. July 2021.
2. Jonibekov J.J. The Role of Computed Tomography in Pneumonia in Patients with Associated Coronavirus Infection // Middle european scientific bulletin, volume 13 june 2021
3. Жонибеков Ж.Ж. Мультимодальная лучевая диагностика пневмонии при новой коронавирусной инфекции (covid-19) // Tibbiyotda yangi kun 2 (34) 2021 г
4. Jonibekov J.J., Ismailova M.Kh. Diagnostic capabilities of ultrasound diagnostics of lung changes in the causative agent of coronavirus infection compared to CT // GCCSA-2021- 6th Global Congress on Contemporary Sciences & Advancements Hosted online from Rome, Italy June 5th, 2021
5. Jonibekov J.J., Ismailova M.Kh. X-RAY examination in pneumonia with the association of covid 19 // GCCSA-2021- 6th Global Congress on Contemporary Sciences & Advancements Hosted online from Rome, Italy June 5th, 2021
6. Jonibekov J.J., Ismailova M.Kh. PREVENTIVE MEASURES ANDMODERN THERAPY OF CORONAVIRUS INFECTION // EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE Vol. 2 No. 1 (2022) EJMMP ISSN: 2795-921X
7. Jonibekov J.J., Ismailova M.Kh. Headache and other Neurological Symptoms in the Structure of the New Clinical Picture Corona Virus Infection (Covid-19) // International Journal of Culture and Modernity ISSN 2697-2131, Volume 12
8. Jonibekov J.J. X-RAY EXAMINATION IN PNEUMONIA WITH THE ASSOCIATION OF COVID 19 // GCCSA-2021- 7th Global Congress on Contemporary Sciences & Advancements Hosted online from, New york, USA www.econferenceglobe.com June 25th, 2021
9. Jonibekov J.J. DIAGNOSTIC CAPABILITIES OF ULTRASOUND DIAGNOSTICS OF LUNG CHANGES IN THE CAUSATIVE // GCCSA-2021- 6th Global Congress on Contemporary Sciences & Advancements Hosted online from Rome, Italy online-conferences.com
10. Ismailova M. X, Jonibekov J. J. PREVENTIVE MEASURES ANDMODERN THERAPY OF CORONAVIRUS INFECTION // EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE Vol. 2 No. 1 (2022) ISSN: 2795-921X. Р.31-35
11. Ismailova M. X, Jonibekov J. J. Headache and other Neurological Symptoms in the Structure of the New Clinical Picture Corona Virus Infection (Covid-19) // International Journalof Cultureand Modernity ISSN 2697-2131, Volume 12 Р.22-32

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Jonibekov Jasurbek Jonibekovich. (2022). GENERAL CHARACTERISTICS OF CLINICAL MATERIAL AND METHODS OF INVESTIGATION OF PATIENTS WITH PNEUMONIA COVID19. Middle European Scientific Bulletin, 25, 200-204. Retrieved from https://cejsr.academicjournal.io/index.php/journal/article/view/1379
  • Submitted
    17 June 2022
  • Revised
    17 June 2022
  • Published
    17 June 2022