GENERAL CHARACTERISTICS OF CLINICAL MATERIAL AND METHODS OF INVESTIGATION OF PATIENTS WITH PNEUMONIA COVID19

Abstract

The main target of SARS CoV-2 is the lungs. In pathogenesis, 2 mechanisms should be distinguished that mutually burden each other and can lead to the development of ARDS (pathomorphologically diffuse alveolar damage): direct viral damage to alveocytes with the development of immuno-inflammatory syndrome; the development of micro- and macrothrombosis of pulmonary vessels and obstructive thrombo-inflammatory syndrome. Therefore, the disease was named microCLOTS – microCOVID Lung Obstructive Trombovascular Syndrome1. As in the whole world, the incidence of COVID 19 pneumonia in the Republic of Uzbekistan is more than 193,000 people, while there is a steady increase.2 The severity and severity of the clinical manifestations of COVID-19 depends on the massiveness of infection (the infecting dose of the virus) on the one hand and the individual characteristics of the macroorganism on the other (age, gender, strength of the immune response, the presence of concomitant diseases-risk factors, etc.). In radiation diagnostics, various variants of changes in the lungs in patients with confirmed coronavirus pneumonia detected using various methods of medical imaging (computed tomography, magnetic resonance imaging, X-ray and ultrasound diagnostics) during primary radiation examination are considered [2.4.6.8.9].